ATTENTION! Amy and Dan Cahill have been located once again, this time in the company of the notoriously unreliable Alistair Oh. Could they have been foolish enough to make an alliance?
Spies report that Amy and Dan seem to be tracking the life of one of the most powerful fighters the world has ever known. If this fearsome warrior was a Cahill, his secrets are sure to be well-guarded . . . and the price to uncover them just might be lethal.
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Some of the oldest and most famous stories in the world – the adventures of Perseus, the labors of Heracles, the voyage of Jason and the Argonauts – are vividly retold in this single, connected narrative of the Heroic Age, from the coming of the Immortals to the first fall of Troy. With fresh dialogue and a brisk pace, the myths of this version are enthrallingly vivid.
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There is no better time to take a look back at the political events of the past 100 years as seen through the eyes of sport and sports people. Ten key international authorities in their respective fields lead you through the most important political elements of contemporary sport.
This book is the first of its kind. It provides a wide ranging perspective through time and place and will be an invaluable tool for students studying sport from an historical and political perspective, and also for those who have a general interest in sport at its interface with politics.
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Covering the latest advances in CNS drug development, this book will guide all those involved in pre-clinical to early clinical trials. The authors describe how recent innovations can accelerate the development of novel CNS compounds, improve early detection of efficacy and toxicity signals, and increase the safety of later-stage clinical trials.
The current crisis in the drug development industry is critically reviewed, as well as the steps needed to correct the problems, including new government-backed regulations and industry-based innovations designed to accelerate CNS drug development in the future.
Animal-based models of major CNS disorders are described in detail, and the ability of the latest in vitro and computer-based models to simulate CNS disease states and predict drug efficacy and side-effects are examined. Particular attention is given to the growing use of biomarkers and how they can be used effectively in early human trials as signals of potential drug efficacy, as well as the increasingly important role of imaging studies to guide dose selection. Cognitive assessments that can be useful indicators of effect in patient populations are also discussed.
Written by a team of clinical scientists involved in CNS drug trials for over 20 years, and based on a wealth of drug development and clinical trial experience, Critical Pathways to Success in CNS Drug Developmentis full of practical advice for successfully designing and executing CNS drug trials, avoiding potential pitfalls, and complying with government regulations
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Thirteen-year-old Dan Cahill and his older sister, Amy, thought they belonged to the world’s most powerful family. They thought the hunt for 39 Clues leading to the source of that power was over. They even thought they’d won. But Amy and Dan were wrong.
One by one, distress calls start coming in from around the globe. Cahills are being kidnapped by a shadowy group known only as the Vespers. Now Amy and Dan have only days to fulfill a bizarre ransom request or their captured friends will start dying. Amy and Dan don’t know what the Vespers want or how to stop them. Only one thing is clear. The Vespers are playing to win, and if they get their hands on the Clues . . . the world will be their next hostage.
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The richly diverse population of the mid-Atlantic region distinguished it from the homogeneity of Puritan New England and the stark differences of the plantation South that still dominate our understanding of early America. In Many Identities, One Nation, Liam Riordan explores how the American Revolution politicized religious, racial, and ethnic identities among the diverse inhabitants of Pennsylvania, Delaware, and New Jersey. Attending to individual experiences through a close comparative analysis, Riordan explains the transformation from British subjects to U.S. citizens in a region that included Quakers, African Americans, and Pennsylvania Germans.
In the face of a gradually emerging sense of nationalism, varied forms of personal and group identities took on heightened public significance in the Revolutionary Delaware Valley. While Quakers in Burlington, New Jersey, remained suspect after the war because of their pacifism, newly freed slaves in New Castle, Delaware, demanded full inclusion, and bilingual Pennsylvania Germans in Easton, Pennsylvania, successfully struggled to create a central place for themselves in the new nation. By placing the public contest over the proper expression of group distinctiveness in the context of local life, Riordan offers a new understanding of how cultural identity structured the early Jacksonian society of the 1820s as a culmination of the American Revolution in this region.
This compelling story brings to life the popular culture of the Revolutionary Delaware Valley through analysis of wide-ranging evidence, from architecture, folk art, clothing, and music to personal papers, newspapers, and local church, tax, and census records. The study’s multilayered local perspective allows us to see how the Revolutionary upheaval of the colonial status quo penetrated everyday life and stimulated new understandings of the importance of cultural diversity in the Revolutionary nation.
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The role and development of sport in Soviet society received little contemporary attention, in the West or in Russia. Although it was widely banned after the Russian Revolution, and viewed as a tool developed by the bourgeoisie for the training of body and mind during the rise of capitalism, the USSR was among the world’s sporting powers. This 1977 book examines the evolution of sport in Russia from its early association with health and hygiene, through a period of functional association with labour and defence, to its post-war importance as a means of enhancing the prestige of Soviet communism abroad. The historical role of Soviet sport is followed from the considerable part that sport played during the period of rapid industrialisation, through its strange fate during the years of mass repression, to its emergence as a major institution after the Second World War.
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The Yupiit in southwestern Alaska are members of the larger family of Inuit cultures. Including more than 20,000 individuals in seventy villages, the Yupiit continue to engage in traditional hunting activities, carefully following the seasonal shifts in the environment they know so well. During the twentieth century, especially after the construction of the trans-Alaska oil pipeline, the Yup’ik people witnessed and experienced explosive cultural changes. Anthropologist Ann Fienup-Riordan explores how these subarctic hunters engage in a “hunt” for history, to make connections within their own communities and between them and the larger world. She turns to the Yupiit themselves, joining her essays with eloquent narratives by individual Yupiit, which illuminate their hunting traditions in their own words. To highlight the ongoing process of cultural negotiation, Fienup-Riordan provides vivid examples: How the Yupiit use metaphor to teach both themselves and others about their past and present lives; how they maintain their cultural identity, even while moving away from native villages; and how they worked with museums in the “Lower 48″ on an exhibition of Yup’ik ceremonial masks. Ann Fienup-Riordan has published many books on Yup’ik history and oral tradition, including Eskimo Essays: Yup’ik Lives and How We See Them, The Living Tradition of Yup’ik Masks and Boundaries and Passages. She has lived with and written about the Yupiit for twenty-five years.
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Adding to a dynamic new wave of scholarship in Atlantic history, The Loyal Atlantic offers fresh interpretations of the key role played by Loyalism in shaping the early modern British Empire. This cohesive collection investigates how Loyalism and the empire were mutually constituted and reconstituted from the eighteenth century onward. Featuring contributions by authors from across Canada, the United States, and the United Kingdom, The Loyal Atlantic brings Loyalism into a genuinely international focus.
Through cutting-edge archival research, The Loyal Atlantic contextualizes Loyalism within the larger history of the British Empire. It also details how, far from being a passive allegiance, Loyalism changed in unexpected and fascinating ways â?? especially in times of crisis. Most importantly, The Loyal Atlantic demonstrates that neither the conquest of Canada nor the American Revolution can be properly understood without assessing the meanings of Loyalism in the wider Atlantic world.
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Best review for The Loyal Atlantic: Remaking the British Atlantic in the Revolutionary Era
